Effects of early enteral nutrition support on prognosis in patients with severe craniocerebral injury
10.3760/cma.j.issn.1008-6706.2014.01.017
- VernacularTitle:早期肠内营养支持对重型颅脑损伤患者预后的影响
- Author:
Liping ZHAI
;
Chunyan LIU
;
Li WANG
;
Jun SU
- Publication Type:Journal Article
- Keywords:
Craniocerebral trauma;
Enteral nutrition;
Immune factors
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(1):37-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of early enteral nutrition on the prognosis of severe head injury patients.Methods According to the different nutritional therapy,160 cases of severe craniocerebral injury patients were randomly divided into two groups using random digit.Two groups of patients were all given similarly conventional methods,the observation group were given early enteral nutrition therapy,the control group were given routine nutrition.CD3+,CD4+,IgE,IgG immune factors were observed after treatment for 10d.Results 10d later,the serum IgG,IgM,IgA in the observation group were significantly higher than those in the conventional nutrition group(t =2.18,3.42,11.23,all P ＜ 0.05),IgE was significantly lower than that in the conventional nutrition group (t =4.76,P ＜ 0.05) ;The serum T-lymphocyte subsets CD3+,CD4+ level in the observation group were higher than those in the conventional nutrition group(t =21.41,5.38,all P ＜ 0.05),the incidence of complications of the observation group was 23.75%,which was significantly lower than 55.00% in the conventional nutrition group(x2 =4.73,P ＜ 0.05).Conclusion Early enteral nutrition therapy can significantly improve the immunity of severe head injury patients,reduce complications,thereby improve the prognosis and the patient's quality of life.
