Study on relationship between TCM syndromes and laboratory indexes of chronic hepatitis B
10.3969/j.issn.1673-4130.2014.05.016
- VernacularTitle:慢性乙型肝炎中医证候与实验室指标的相关性研究
- Author:
Feifei LI
;
Lei WANG
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
hepatitis B,chronic;
symptom complex;
laboratory techniques and procedures
- From:
International Journal of Laboratory Medicine
2014;(5):545-546
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship between traditional Chinese medicine (TCM ) syndromes and the laboratory in-dexes in chronic hepatitis B .Methods According to the TCM syndrome differentiation ,145 cases of chronic hepatitis B were divid-ed into the 5 syndromes :the stagnation of damp-heat in middle-jiao ,the stagnation of liver-QI and deficiency of the spleen ,the spleen-kidney Yang deficiency ,the collaterals obstruction by blood stasis and the liver-kidney Yin deficiency .The correlation be-tween the TCM syndromes and the laboratory indexes was observed .Results The research found that the stagnation of damp-heat in middle-jiao and the stagnation of liver-QI and deficiency of the spleen had the highest proportion in the five kinds of the CM syn-dromes ,which accounted for 53 .8% and 31 .7% ,respectively ;The positive rates of total bile(TBil) and indirect bile(IBil) in the stagnation of damp-heat in middle-jiao were 69 .4% and 68 .8% respectively ,which were significantly higher than those in other 3 groups (P<0 .05);However ,the positive rates of total bile acid (TBA) ,alanine aminotransferase(ALT ) and HBeAg in the liver-kidney Yin deficiency were higher than those in other 3 groups .The HBV-DNA viral load in the stagnation of damp-heat in middle-jiao was significantly higher than that in other 3 groups (HBV-DNA>105 copies/mL) ,and the HBV replication was most active . Conclusion There are some relationships between the TCM syndromes and the laboratory indexes in chronic hepatitis B ,therefore the laboratory indexes have more important clinical significance for the syndrome differentiation and treatment of chronic hepatitis B .
