Clinical significance of detecting levels of serum and ascitic PCT in patients with liver cirrhosis complicating spontaneous bacterial peritonitis

VernacularTitle:肝硬化合并自发性腹膜炎患者血清和腹水降钙素原检测的意义
Author: Fei XIE ; Zhixiang LIU ; Li CHEN
Publication Type:Journal Article
Keywords: procalcitonin; liver cirrhosis; peritonitis
From: International Journal of Laboratory Medicine 2014;(5):525-526
CountryChina
Language:Chinese
Abstract: Objective To study the changes of serum and ascitic procalcitonin (PCT ) level in the patients with liver cirrhosis complicating spontaneous bacterial peritonitis (SBP) and to investigate the value in its early diagnosis .Methods 92 patients with cirrhotic and ascites were detected the levels of serum and ascitic PCT by the immunofluorescence method and the detection results were compared with the ascites routine and the bacterial culture results .Results Serum levels of PCT in the SBP group and the non-SBP group were obviously higher than those in the control group ,the difference was statistically significant (P<0 .05);Serum and ascitic levels of PCT in the SBP were significantly higher than those in the non-SBP group ;The sensitivity of serum PCT for di-agnosing peritonitis was 89 .3% ,the sensitivity of ascitic PCT for diagnosing peritonitis was 71 .4% .Conclusion The levels of ser-um and ascitic PCT have the important value for the early diagnosis of liver cirrhosis ascites ,moreover serum PCT level has higher value for early diagnosing liver cirrhosis ascites .