The clinical value of IgG antibodies avidity index detection in pregnant women with TORCH infection

VernacularTitle:TORCH 感染孕妇IgG 亲和力检测的临床价值
Author: Dongsheng WU ; Yuanjian WU ; Yalu REN ; Liuhong WANG
Publication Type:Journal Article
Keywords: human prenatal and postnatal care virus; microarray enzyme-linked immunosorbent assay; pregnant women
From: International Journal of Laboratory Medicine 2014;(5):538-539
CountryChina
Language:Chinese
Abstract: Objective To explore the relationship between the type of TORCH infection and pregnancy outcome through the de-tection of TORCH infection in pregnant women with IgG avidity index (AI) .Methods Collected each type of TORCH pathogens IgM positive maternal serum ,and detect the IgG avidity index and track the outcome of pregnancy .Results The rate of TORCH pathogens recent infection (AI<30% )in pregnant women ,HSV ,RUB ,CMV ,TOXO respectively were 0 ,3 .8% ,9 .3% ,7 .9% ;In the group of pregnant women with TORCH-IgG AI<30% ,there were 2 cases of pregnancy outcome of abnormal (missed abortion) and one case of fetal malformations (hydrocephalus) .Conclusion In the recent infection of TORCH pathogens in pregnant women , mainly are non-primary infection ;The damage of cytomegalovirus and Toxoplasma gondii primary infection to the fetus is much larger than the non-primary infection .