Review on Study of Anti-tumor of Raddeanin A
- VernacularTitle:竹节香附素A抗肿瘤研究进展
- Author:
Gang XUE
;
Xi ZOU
;
Ruiping WANG
- Publication Type:Journal Article
- Keywords:
Raddeanin A;
cancer;
anti-tumor activity;
structure;
cellapoptosis
- From:
Journal of Zhejiang Chinese Medical University
2014;(2):224-226
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To review the antitumor progress of Raddeanin A in nearly 10 years. [Method] Col ecting the antitumor research literature about Raddeanin A for nearly 10 years, describing its antitumor research mechanism, such as inducting of cellapoptosis blocking the cellcycle, blocking STATs signaling pathways and inhibiting the tumor angiogenesis. [Result] Raddeanin A could induce the H460 cellapoptosis, block LoVo cellcycle and STATs signaling pathways of LoVo cells, and inhibit HepG-2 cellangiogenesis. [Conclusion] The antitumor mechanism of Raddeanin A could be inducting of cellapoptosis, blocking the cellcycle, blocking STATs signaling pathways and inhibiting the tumor angiogenesis.
