Correlation of High Sensitivity C-reactive Protein and Fibrinogen with Carotid Artery Arteriosclerosis of Patients with Cerebral Infarction
- VernacularTitle:超敏C反应蛋白、纤维蛋白原与脑梗死患者颈动脉粥样硬化的相关性分析
- Author:
Dan WANG
;
Fu ZHENG
;
Qin HUANG
;
Li ZHANG
;
Tao WEI
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Carotid artery arteriosclerosis;
High sensitivity C-reactive protein;
Fibrinogen
- From:
Journal of Kunming Medical University
2014;(1):80-83
- CountryChina
- Language:Chinese
-
Abstract:
Objective The purpose of this study was to investigate the correlation of high sensitivity C-reactive protein (hsCRP) and fibrinogen with carotid artery arteriosclerosis of patients with cerebral infarction. Methods One hundred and thirteen patients with cerebral infarction were assigned as study group, and 102 healthy persons as control group. The levels of serum hsCRP and Fib in the two groups were measured. The carotid artery arteriosclerosis and carotid intimal-medial thickness (IMT) were examined by color Doppler and B-ultrasound. Results The value of IMT between study group and control group was statistically significant. The positive rates of carotid artery arteriosclerosis plaque and vulnerable plaque in study group were significantly higher than those in control group (all<0.05) . The level of serum hsCRP was significantly higher in study group than that of control ( <0.05) . The level of serum Fib between study group and control group was not statistically significant ( >0.05) . Conclusion The level of hsCRP was closely related to the degree of carotid artery arteriosclerosis and the occurrence and development of cerebral infarction. But the level of Fib was not closely related to the degree of carotid artery arteriosclerosis.
