Effects of microsurgical technique treatment on acknowledge ability,activities of daily living, cortex blood perfusion and neuropeptide levels of brain glioma patients
10.3969/j.issn.1671-8348.2014.05.009
- VernacularTitle:显微手术对87例脑胶质瘤患者认知、生活能力及血流灌注和神经肽水平的影响
- Author:
Zulu SU
;
Haohao CHEN
;
Hai SU
;
Yi ZHANG
- Publication Type:Journal Article
- Keywords:
microsurgery;
brain glioma;
acknowledge ability;
activities of living;
blood perfusion;
neuropeptide
- From:
Chongqing Medicine
2014;(5):534-536
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of microsurgical technique treatment on acknowledge ability ,activities of daily liv-ing ,cortex blood perfusion and neuropeptide levels of brain glioma patients .Methods Microsurgical technique treatment and tradi-tional operation were given to 87 brain glioma patients ,respectively .The acknowledge ability and activities of daily living were measured by HDS ,MMSE and ADL ;the cortex blood perfusion were revealed by PET ,and the neuropeptide levels including argi-nine vasopressin ,oxytocin ,β-endorphin ,somatostatin and neurotensin of patients from two different surgical groups were compared . Results As compared with the traditional operation ,the acknowledge ability and activities of daily living of patients from microsur-gical treatment group were significantly improved(P<0 .05) ,the cortex blood perfusion were statistically increased (P<0 .05) and the levels of five kinds of neuropeptide were all profoundly increased (P< 0 .05) .Conclusion Microsurgical technique treatment could improve the acknowledge ability and activities of daily living of brain glioma patients ,the mechanisms of which could be the increase of cortex blood perfusion and theincrease of neuropeptide levels .