Analysis of the influence factors of blastomere damage of frozen thawed embryos
10.3969/j.issn.1671-8348.2014.05.018
- VernacularTitle:冷冻复苏胚胎卵裂球损伤因素分析
- Author:
Wenbin WU
- Publication Type:Journal Article
- Keywords:
vacuole;
blastomere damage;
blastomere number;
embryo fragment
- From:
Chongqing Medicine
2014;(5):558-560
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the factors that affect cryosurvival of frozen-thawed embryos .Methods A retrospective study was conducted on 98 patients undergoing FET with two embryos of which one was complete cryosurvival and the other not .1∶1 matched samples logistic regression analysis was employed to observe the influence of cytoplasm with granulation ,vacuolar cyto-plasm ,embryo fragments ,blastomere number and equality of size on the cryosurvival of frozen-thawed embryos .Results Presence of vacuolar cytoplasm(OR=13 .413) or embryo fragments(OR= 1 .101) significantly increased blasstomere damage ,but the in-creased blastomere number(OR=0 .569) decreased it(P<0 .05) .Conclusion Embryos with vacuolar cytoplasm ,or embryo frag-ments and blastomere number are very vital factors that affect the blastomere damage after cryopreservation .
