Antibacterial mechanism and safety of zinc oxide
10.3969/j.issn.2095-4344.2014.03.023
- VernacularTitle:氧化锌的抗菌机制及其安全性研究进展
- Author:
Rong XIANG
;
Dongbo DING
;
Liangliang FAN
;
Xiaozhong HUANG
;
Kun XIA
- Publication Type:Journal Article
- Keywords:
biocompatible materials;
zinc oxide;
review;
nanoparticles
- From:
Chinese Journal of Tissue Engineering Research
2014;(3):470-475
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Zinc oxide has shown extraordinary antibacterial effect. But the antibacterial mechanisms of zinc oxide have not been wel developed, and the safety of zinc oxide has not yet been confirmed.
OBJECTIVE:To summarize the antibacterial mechanism and safety of zinc oxide based on the current research situation of zinc oxide.
METHODS:The CNKI database and PubMed database (2005-01/2013-08) were used to search the related articles about zinc oxide antibacterial mechanism and safety. The retrieval keywords were“zinc oxide or ZnO, antibacterial”,“zinc oxide or ZnO, safety”both in English and Chinese.
RESULTS AND CONCLUSTION:The antibacterial mechanism of zinc oxide is complex. Zinc oxide reveals its antibacterial power by photo catalysis, zinc ion dissolve out, and active oxygen. But the relationship between photo catalysis and active oxygen is different based on different studies. The safety of zinc oxide is not confirmed, and different studies have different results. Especial y for the nano-zinc oxide, some studies have showed that the zinc oxide is toxic. Al of these mean much more researches are needed to verify the safety of zinc oxide.
