Comparison and selective preference of preparation methods of platelet-rich gel
10.3969/j.issn.2095-4344.2014.03.024
- VernacularTitle:富血小板凝胶制备方法的比较与优选
- Author:
Jian KANG
;
Wen YUAN
- Publication Type:Journal Article
- Keywords:
biocompatible materials;
blood platelets;
gels;
review
- From:
Chinese Journal of Tissue Engineering Research
2014;(3):476-481
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Platelet-rich plasma gel contains some kinds of growth factors, which play important roles in repair of local trauma and bone defects. Platelet-rich plasma gel is now more and more studied as tissue engineering scaffolds, but there are no unified preparation methods.
OBJECTIVE:To summarize the studies about the preparation methods of platelet-rich plasma gel and the growth factors in platelet-rich plasma gel in recent years, and to compare different methods in order to find which one is better.
METHODS:A online search of PubMed database from January 1980 to January 2013 and China National Knowledge Infrastructure from January 1980 to January 2013 was performed with the key words of“platelet-rich plasma, platelet-rich plasma gel, tissue engineering”in English and Chinese, respectively. The studies about detection and preparation methods of platelet-rich plasma were included and those unrelated to platelet-rich plasma were excluded. Final y, 322 articles were gained and 67 articles were included in result analysis.
RESULTS AND CONCLUSION:Al preparation methods have their advantages. We should select the suitable method according to the goal of study. With the further study of platelet-rich plasma, it wil become more and more important for bone defect repair and tissue engineering research.