Maspin gene and the invasion and metastasis of gastric cancer
10.3760/cma.j.issn.1673-422X.2014.03.015
- VernacularTitle:Maspin基因与胃癌侵袭转移
- Author:
Haipeng LIANG
;
Qingwei YANG
- Publication Type:Journal Article
- Keywords:
Maspin gene;
Stomach neoplasms;
Neoplasm invasiveness;
Neoplasm metastasis
- From:
Journal of International Oncology
2014;41(3):209-211
- CountryChina
- Language:Chinese
-
Abstract:
The maspin gene,a tumor suppressor gene and a member of the serpin superfamily,is isolated from mammary epithelial cells.Maspin gene plays an important role in the process of invasion and metastasis of gastric cancer.Researches show that maspin gene suppresses the occurrence,development and metastasis of gastric cancer mainly by inducing tumor cell apoptosis,inhibiting tumor angiogenesis,methylation modification,promoting homogeneity adhesion and inhibiting heterogeneous adhesion.
