Research progress on human epidermal growth factor receptor-2 in gastric cancer
10.3760/cma.j.issn.1006-9801.2014.01.020
- VernacularTitle:人表皮生长因子受体2基因与胃癌关系的研究进展
- Author:
Dong WANG
- Publication Type:Journal Article
- Keywords:
Gastric neoplasms;
Human epidermal growth factor receptor-2;
Gene amplification
- From:
Cancer Research and Clinic
2014;26(1):64-66
- CountryChina
- Language:Chinese
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Abstract:
Amplification and overexpression of human epidermal growth factor receptor-2 (HER-2) gene are bound up with the process and the prognosis of gastric cancer.Meanwhile,recent researches have shown the great significance of HER-2 co-amplification with other genes in gastric cancer.Therefore,detection of HER-2 gene gradually becomes the basis of gastric cancer diagnosis,and it is one of the important targets in the treatment of gastric cancer.This article will review the gene amplification and co-amplification of HER-2 in the progress,prognosis,diagnosis and treatment of gastric cancer.
