The research of the brucea javanica oil emulsion combined with the whole radiotherapy in non-small cell lung cancer patients with brain metastasis
10.3760/cma.j.issn.1006-9801.2013.12.014
- VernacularTitle:鸦胆子油乳配合全脑放疗对非小细胞肺癌脑转移效果的临床观察
- Author:
Jing WANG
;
Jie LI
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-lung;
Brucea javanica oil emulsion;
Radiotherapy;
Neoplasms brain metastasis
- From:
Cancer Research and Clinic
2013;25(12):835-837
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy between the brucea javanica oil emulsion combined with the whole radiotherapy group (treatment group) and only radiotherapy group (control group) in non-small cell lung cancer patients with brain metastases.Methods The clinical data of 53 non-small cell lung cancer patients with brain metastasis were retrospectively reviewed,including 27 cases in treatment group and 26 cases in control group.Results The remission rates were 77.8 ％ (21/27) and 69.2 ％ (18/26) respectively in treatment group and control group.The improvement rates of Kamofsky in the treatment group and control group were 66.7 ％ (18/27) and 30.8 ％ (8/26),the stable rates were 22.2 ％ (6/27) and 30.8 ％ (8/26),the decrease rates were 11.1％ (3/27) and 38.5 ％ (10/26).The remission rates of clinical sympotoms were 92.6 ％ (25/27) and 69.2 ％ (18/26) respectively in treatment group and control group.The difference of remission rate between two groups has no statistic significance (P ＞ 0.05),while the difference of the quality of life and clinical sympotoms between two groups were significant respectively (P ＜ 0.05).Conclusion The brucea javanica oil emulsion combined with the whole radiotherapy can relieve clinical sympotoms and improve the quality of life of patients,and may play a role on improving the effect of radiotherapy.
