Research progress of Dab2 gene in cancers
10.3760/cma.j.issn.1006-9801.2013.12.020
- VernacularTitle:Dab2基因与肿瘤相关性的研究进展
- Author:
Xuemei XIE
- Publication Type:Journal Article
- Keywords:
Dab2 gene;
Neoplasms
- From:
Cancer Research and Clinic
2013;25(12):847-850
- CountryChina
- Language:Chinese
-
Abstract:
The human Dab2 gene has a variety of physiological functions,and plays important roles in various signal transduction pathways.Researches have shown that reduced expression of Dab2 was closely related to the occurrence and development in many malignant cancers,and Dab2 has been regarded as a tumor suppressor.This paper reviewed about multiple researches on the structure and functions of Dab2,and explored the specific mechanisms in oncogenesis.
