Early life stress and schizophrenia:a retrospective case-control study
10.3760/cma.j.issn.1671-7368.2014.01.025
- VernacularTitle:儿童期受虐待经历与精神分裂症相关性的问卷调查
- Author:
Shilin CAO
;
Guoqiang TIAN
;
Shenglin LIANG
;
Haichao JIANG
;
Jianguang GAN
;
Chao QIAN
;
Zhengquan XU
- Publication Type:Journal Article
- Keywords:
Early life stress;
Schizoprenia
- From:
Chinese Journal of General Practitioners
2014;13(1):67-69
- CountryChina
- Language:Chinese
-
Abstract:
A total of 105 patients with first-episode schizophrenia (male =51,female =54) and 99 normal controls (male =51,female =48) were included into this retrospective case-control study.Childhood trauma questionnaire-28 item short form (CTQ-SF) was used to assess the experience of childhood abuse.The result of binary logistic regression showed that emotional abuse (β =0.630,P ＜ 0.05) and emotional neglect(β =0.270,P ＜ 0.05) were included into the final model of predicting schizophrenia.It indicates that patients with first-episode schizophrenia experienced more early life stress than controls.Particularly emotional abuse and emotional neglect may play important roles in the onset of schizophrenia.
