Clinical study of intrapleural cycle hyperthermic perfusion chemotherapy in the treatment of malignant pleural effusion
10.3760/cma.j.issn.1671-7368.2014.01.019
- VernacularTitle:胸腔循环热灌注化疗治疗恶性胸腔积液临床研究
- Author:
Lijuan WANG
;
Hongqiao ZHANG
;
Nan BA
;
Peili LI
;
Xixiu YE
;
Jianyuan LI
;
Min WU
- Publication Type:Journal Article
- Keywords:
Iung neoplasms;
Treatment outcome
- From:
Chinese Journal of General Practitioners
2014;13(1):53-54
- CountryChina
- Language:Chinese
-
Abstract:
Malignant pleural effusion is a common complication of advanced cancer.The present study employed chest circulating hot infusion chemotherapy for 55 cases of malignant pleural effusion.The outcomes were complete remission (n =23,41.8％),partial remission (n =25,45.5％),stable disease (n=4,7.3 ％) and progressive disease (n =3,5.5％).And the effective rate was 87.3％.After treatment,the levels of interleukin-10 (IL-10) and interleukin-6 (IL-6) were significantly lower than those before treatment (P ＜ 0.05).And the levels of interleukin-2 (IL-2) and interferon-gamma (IFN-γ) were significantly higher than those before treatment (P ＜ 0.05).Pleural circulation perfusion chemotherapy is both safe and effective in the treatment of malignant pleural effusion.And it helps to enhance immune functions and improve the quality-of-life of patients.
