Interstitial infiltration pattern in early morphea: clinicopathological analysis of 25 cases
10.3760/cma.j.issn.0412-4030.2014.01.015
- VernacularTitle:25例早期硬斑病的间质性浸润模式分析
- Author:
Hao CHEN
;
Yiqun JIANG
;
Xiulian XU
;
Xuesi ZENG
;
Jianfang SUN
- Publication Type:Journal Article
- Keywords:
Scleroderma,localized;
Histology;
Inflammation;
Cells
- From:
Chinese Journal of Dermatology
2014;47(1):51-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective To estimate the diagnostic value of interstitial infiltration pattern for early morphea.Methods Twenty-five cases of early morphea pathologically characterized by interstitial infiltration of inflammatory cells were collected from 2010 to 2012.The clinicopathological features of these cases were retrospectively analyzed.Results The average clinical course was 7.5 months.The primary manifestation was edematous dark erythematous plaques,and interstitial or mixed infiltrate of inflammatory cells was the characteristic histopathological presentation.After anti-inflammatory treatment,lesions markedly improved or disappeared in 70％ of these patients.Conclusions Interstitial infiltration of inflammatory cells is a rare histologic pattern in early morphea.To learn and recognize this pattern may be beneficial to the diagnosis and treatment of early morphea.
