Characteristics of thyroid nodules in middle-age to very elderly subjects
10.3760/cma.j.issn.1000-6699.2014.02.007
- VernacularTitle:中年至超高龄老年人甲状腺结节的发病特点
- Author:
Lei QIU
;
Mingxiao SUN
;
Yao WANG
;
Yajing SHANG
- Publication Type:Journal Article
- Keywords:
Thyroid nodules;
Ultrasonography;
Age;
Thyroid function
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(2):115-118
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and characteristics of thyroid nodule and its relationship with thyroid function in a group of middle-aged to elderly individuals.Methods A cross-sectional,stratified,and cluster random sampling study was performed in 1 721 subjects (average age 71.4 years,from 40 to 108 years).All subjects underwent ultrasound thyroid scan,and the prevalence of thyroid nodule and its size,quantity,property,and distribution were age-stratified and analyzed.The relationship between nodule existence and thyroid function was assessed in subjects who randomly accepted TSH,FT4,and FT3 tests.Results The prevalence of thyroid nodule reached to 76.6%.The incidence of nodule increased with age (x2 =92.08,P<0.01),and was more common in female (87.4% vs 75.5%,P =0.001).In patients with thyroid nodule,the prevalence of solitary nodule was 25%,compared with 75% of multiple nodules,which increased with age (x2 =78.55,P<0.01).The prevalence of small nodule reached to 68.2%,compared with 31.8% of large nodules,which also increased with age (x2 =36.82,P<0.01).As to the property of nodule,solid nodule was the most common form (72.3 %),cyst-solid nodule accounted for 26.6%,and detection rate of cyst nodule was only 2.1%,and there was no significant difference among the different age groups (x2 =14.22,P=0.076).884 among the total subjects underwent thyroid function test,multiple logistic regression analysis demonstrated that the reduction of TSH was the only independent predicting factor of thyroid nodule (P =0.005).Conclusions The prevalence of thyroid nodules was considerably high according to the examing of ultrasonographic image,especially in the elderly.The incidence of thyroid nodule,especially multiple nodules or larger nodule,increased with age and solid nodule was the most common finding.