Research progress in microsomal triglyceride transfer protein and non-alcoholic fatty liver disease
10.3760/cma.j.issn.1000-6699.2014.01.020
- VernacularTitle:微粒体甘油三酯转运蛋白与非酒精性脂肪性肝病的研究进展
- Author:
Linshan ZHANG
;
Xin GAO
- Publication Type:Journal Article
- Keywords:
Microsomal triglyceride transfer protein;
Non-alcoholic fatty liver disease;
Gene polymorphism
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(1):76-78
- CountryChina
- Language:Chinese
-
Abstract:
Microsomal triglyceride transfer protein (MTP) is a key transfer protein in lipid metabolism and is mainly expressed in the hepatocytes and enterocytes.It plays an important role in transferring triglyceride as well as in assembly and secretion of very low density lipoprotein.Recent studies have shown that MTP is closely related to the onset and development of non-alcoholic fatty liver disease.