Therapeutic effects of acute normovolemic hemodilution replacing autologous blood donation used in coronary artery bypass graft surgery in elderly patients

VernacularTitle:急性等容血液稀释自体输血应用于老年人冠状动脉旁路移植手术的初步探讨
Author: Huaibin WANG ; Wenjun ZHEN ; Xiaokang OUYANG ; Yujian MA ; Wenqi LUO ; Jie TAN
Publication Type:Journal Article
Keywords: Hemodilution; Coronary artery bypass,off-pump
From: Chinese Journal of Geriatrics 2014;33(1):29-31
CountryChina
Language:Chinese
Abstract: Objective To investigate effects of acute normovolemic hemodilution (ANH) used in coronary artery bypass graft (CABG) surgery in elderly patients.Methods 60 elderly patients (aged ≥65 years) received CABG surgery under cardiopulmonary bypass,of which 30 patients using ANH techniques and 30 patients without ANH techniques.Results All patients were revascularized completely with stable surgical procedure,no serious complications and no operative mortality were found.Oxygen supplying was balanced with demanding,without tissue hypoxia.Indicators of the myocardial protective effect,coagulation,liver function,kidney function,glucose metabolism,negative nitrogen balance,and postoperative drainage volume were not significantly different between the two groups (P＞0.05).Allogeneic blood transfusion volume was significantly lower in study group than in control group[(0.9±0.9)U vs.(2.5±1.2)U,t=2.704,P＜0.01].Conclusions The ANH technique used in CABG operation in appropriate elderly patient is feasible and safe,with satisfactory clinical results.