Observation on efficacy of endoscopic submucosal dissection and endoscopic mucosal resection in the therapy of esophageal mucosal disease
10.3760/cma.j.issn.1673-4904.2014.07.019
- VernacularTitle:内镜下黏膜剥离术和内镜下黏膜切除术治疗食管黏膜病变的疗效比较
- Author:
Hongjian JIANG
;
Huanqing WU
;
Xuejin LI
;
Wenliang HAN
;
Chunling ZHAO
- Publication Type:Journal Article
- Keywords:
Endoscopic submucosal dissection;
Endoscopic mucosal resection
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(7):54-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the outcome and safety of endoscopic submucosal dissection (ESD) versus endoscopic mucosal resection (EMR) in the management of esophageal mucosal lesion.Methods The clinical data of 70 patients with esophageal mucosal lesion were analyzed.Twenty-five patients were treated by ESD (ESD group) and 45 patients were treated by EMR (EMR group).The enbloc resection rate,tissue healing resection rate,operation time,complication and recurrence rate were compared between two groups.Results The enbloc resection rate,tissue healing resection rate in ESD group were significantly higher than those in EMR group [60.0％(15/25) vs.48.9％(22/45),48.0％(12/25) vs.40.0％ (18/45)] (P ＜0.05).The local recurrence rate in ESD group was lower than that in EMR group [4.0％ (1/25) vs.20.0％ (9/45)] (P ＜ 0.05).The severe complication such as delayed hemorrhage,perforation,stenosis between two groups had no significant difference (P ＞ 0.05).The operation time in ESD group was (64.3 ±27.1) min,and significantly longer than that in EMR group [(27.6 ± 14.1) min] (P ＜0.05).Conclusions Compare with EMR,ESD has better enbloc resection rate,tissue healing resection rate,and lower recurrence rate.It is more safe and effective in the therapy of esophageal mucosal disease.
