The accuracy of functional magnetic resonance imaging and contrast-enhanced ultrasound on evaluation of breast cancer patients after neoadjuvant chemotherapy
10.3760/cma.j.issn.1673-4904.2014.08.008
- VernacularTitle:乳腺癌患者新辅助化疗后核磁共振功能成像与超声造影检查对于疗效评价的准确性探讨
- Author:
Rongrong CUI
;
Cheng XU
;
Xiaoling LU
;
Xiaoming ZUO
;
Xiaoyan LIN
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Magnetic resonance imaging;
Pathology;
Contrast-enhanced ultrasound;
Neoadjuvant chemotherapy
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(8):24-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the accuracy of functional magnetic resonance imaging(fMRI) and contrast-enhanced ultrasound on evaluation of the breast cancer patients after neoadjuvant chemotherapy.Methods Forty-eight patients with breast cancer who were confirmed by biopsy,undergoing 4 cycles weekly dose-concentrated programs (wPC) neoadjuvant chemotherapy,evaluated the efficacy by fMRI and contrastenhanced ultrasound.Results In pathology,complete remission was 12 cases (25.0％,12/48),non remission was 13 cases (27.1％,13/48).In contrast-enhanced ultrasound,complete remission was 20 cases (41.7％,20/48),non remission was 10 cases (20.8％,10/48).In fMRI,complete remission was 17 cases (35.4％,17/48),non remission was 11 cases (22.9％,11/48).The P values more than 0.05 showed no statistically significant among three methods,the Kappa test showed that fMRI were superior to contrastenhanced ultrasound on evaluating the efficacy of neoadjuvant chemotherapy.Conclusions fMRI and contrast-enhanced ultrasound can be used in evaluating the efficacy of neoadjuvant chemotherapy,however,the data shows fMRI is superior to contrast-enhanced ultrasound.Contrast-enhanced ultrasound must be as the supplementary method.
