The performance of △POP in the assessment of fluid responsiveness in septic shock patients in emergency department

VernacularTitle:脉搏血氧波形振幅变异率在急诊感染性休克患者容量复苏中的作用
Author: Yecheng LIU ; Jun XU ; Huadong ZHU ; Zhong WANG ; Xuezhong YU
Publication Type:Journal Article
Keywords: Fluid responsiveness; Septic shock; Emergency department
From: Chinese Journal of Emergency Medicine 2014;23(1):15-18
CountryChina
Language:Chinese
Abstract: Objective Respiratory variations in the pulse oximetry plethysmographic waveform amplitude (△POP) have been popularly studied as a dynamic indicators for fluid responsiveness assessment.The authors hypothesized that △POP can indicate fluid responsiveness in septic shock patient in emergency department.Methods A prospective study of 28 patients with septic shock was carried out in Emergency Room and Emergency Intensive Care Unit from 1 October,2010 to 30 September,2011.Hemodynamic data including cardiac index,stroke volume Variation (SVV) and △POP were recorded before and after volume expansion treatment.Fluid responsiveness was defined as an increase in cardiac index of 15％ or greater.Results Changes in △POP after volume expansion were greater in responders than that in non-responders (P ＜ 0.01).There was a significant relation between △POP and SVV before volume expansion (r =0.900,P ＜ 0.0001).Conclusions △POPcan indicate fluid responsiveness non-invasively in septic shock patient in emergency department.This marker has potential clinical application with high sensitivity and reliability.