CD44:a cancer stem cell biomarker functioning from the surface to the center
10.3760/cma.j.issn.1673-4203.2014.02.015
- VernacularTitle:CD44:由表及里的肿瘤干细胞标志物
- Author:
Yuan GAO
;
Bai RUAN
;
Zhuochao ZHANG
;
Weihui LIU
;
Kefeng DOU
- Publication Type:Journal Article
- Keywords:
CD44;
Neoplasms stem cells;
Hyaluronic acid;
EMT;
MicroRNAs
- From:
International Journal of Surgery
2014;41(2):119-122
- CountryChina
- Language:Chinese
-
Abstract:
With the continuous development of the cancer stem cell theory,biomarkers for CSCs (Cancer stem cells) have gradually become the hot issues in tumor research.As the most commonly used CSCs biomarker,CD44 gains lots of attentions.This paper will review recent research about CD44 molecule and its powerful role in regulating tumor progenesis and progression.