Percutaneous transhepatic variceal embolization with 2-Octyl-Cyanoacrylate versus endoscopic cyanoacrylate injection for treatment of gastric variceal bleeding
10.3760/cma.j.issn.1007-5232.2013.05.009
- VernacularTitle:经皮经肝组织胶栓塞术与内镜下注射对治疗胃静脉曲张破裂出血的疗效比较
- Author:
Lei WU
;
Hua FENG
;
Jinhua HU
;
Guangchuan WANG
;
Yi CUI
;
Chunqing ZHANG
- Publication Type:Journal Article
- Keywords:
Gastric varices;
Embolization,therapeutic;
Tissue adhesives;
Hemorrhage
- From:
Chinese Journal of Digestive Endoscopy
2013;30(5):273-276
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of a modified percutaneous transhepatic variceal embolization (PTVE) with 2-Octyl-Cyanoacrylate (2-OCA) and endoscopic variceal obturation (EVO) in preventing gastric variceal bleeding.Methods Seventy-seven patients with history of gastric variceal bleeding who underwent either EVO or PTVE were retrospectively reviewed.The rebleeding rate,survival rate and complications were compared between the two groups.Results EVO was performed in 45 patients; PTVE was performed in 32 patients.During the follow-up (19.78 ± 7.70 months in EVO group,vs.21.53 ± 8.56 months in PTVE group),rebleeding occurred in 17 patients (37.78%) of EVO group,and in 4 patients (12.5%) of PTVE group (P =0.028).The cumulative rebleeding free rate for EVO was 75%,59%,and 49% in 1,2,and 3 years,respectively; 93%,84%,84% for PTVE (P =0.011).There is no significant different in survival rate and the incidence of complications was similar in two groups.Conclusion Compared with EVO,PTVE with 2-OCA demonstrates advantage as an effective and safe method for gastric varices.