Analysis of occurrence and risk factors of chronic kidney disease in the ICU patients
10.3760/cma.j.issn.1001-7097.2013.09.004
- VernacularTitle:重症监护室患者发生慢性肾脏病的病因及危险因素分析
- Author:
Yuhong ZHAO
;
Kaiqiang JI
;
Bin ZANG
;
Detian LI
- Publication Type:Journal Article
- Keywords:
ICU;
Chronic kidney disease;
Risk factor
- From:
Chinese Journal of Nephrology
2013;29(9):660-664
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the occurrence and clinical features of chronic kidney disease (CKD) in the ICU patients and identify the possible risk factors.Methods A retrospective study was performed in 2281 ICU patients enrolled from Shengjing hospital between January 2007 and December 2010,in which 1860 cases had complete data and were followed-up,the other 421 cases were excluded for the reasons of dying,suffering from CKD originally,lacking complete data and missing.The cases were divided into CKD and non-CKD groups according to SCODRED and CKD diagnosis standards.Assessment was performed to screen risk factors of CKD.Results There were obvious differences between CKD and non-CKD groups at age,pregnancy,AKI and liver function (P <0.05).The CKD's annual morbidity rate of ICU patients was 20%-30%,and the incidence showed an increasing trend with time.Age,pregnancy,AKI,APACHE-Ⅱ score,invasive diagnosis and treatment,mechanical ventilation,organ failure and kidney-hurt drugs were risk factors for CKD in the ICU patients.Conclusions The morbidity rate of CKD in the ICU patients is high,and the number of CKD patients show an increasing trend with time.Age,APACHE-Ⅱ score > 15,the number of failed organs ≥2,the variety of kidney-hurt drug≥2,pregnancy,AKI,the number of invasive diagnosis and treatment≥3,mechanical ventilation are independent risk factors of CKD in the ICU patients.