Clinical Practice Guideline for Accurate Diagnosis and Effective Treatment of Gastrointestinal Stromal Tumor in Korea.
10.3346/jkms.2010.25.11.1543
- Author:
Yoon Koo KANG
1
;
Kyoung Mee KIM
;
Taesung SOHN
;
Dongil CHOI
;
Hye Jin KANG
;
Min Hee RYU
;
Woo Ho KIM
;
Han Kwang YANG
Author Information
1. Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. ykkang@amc.seoul.kr
- Publication Type:Review ; Practice Guideline
- Keywords:
Guideline;
Gastrointestinal Stromal Tumors;
Diagnosis;
Surgery;
Treatment;
Chemotherapy, Targeted;
Imatinib;
Sunitinib
- MeSH:
Antineoplastic Agents/therapeutic use;
Gastrointestinal Stromal Tumors/*pathology/surgery/*therapy;
Humans;
Neoadjuvant Therapy;
Piperazines/therapeutic use;
Proto-Oncogene Proteins c-kit/metabolism;
Pyrimidines/therapeutic use;
Recurrence;
Republic of Korea;
Tumor Markers, Biological/metabolism
- From:Journal of Korean Medical Science
2010;25(11):1543-1552
- CountryRepublic of Korea
- Language:English
-
Abstract:
Despite the rarity in incidence and prevalence, gastrointestinal stromal tumor (GIST) has emerged as a distinct pathogenetic entity. And the clinical management of GIST has been evolving very rapidly due to the recent recognition of its oncogenic signal transduction pathway and the introduction of new molecular-targeted therapy. Successful management of GIST requires a multidisciplinary approach firmly based on accurate histopathologic diagnosis. However, there was no standardized guideline for the management of Korean GIST patients. In 2007, the Korean GIST study group (KGSG) published the first guideline for optimal diagnosis and treatment of GIST in Korea. As the second version of the guideline, we herein have updated recent clinical recommendations and reflected changes in diagnosis, surgical and medical treatments for more optimal clinical practice for GIST in Korea. We hope the guideline can be of help in enhancing the quality of diagnosis by members of the Korean associate of physicians involving in GIST patients's care and subsequently in achieving optimal efficacy of treatment.
