"Re-evaluation of ""Shanghai Criteria"": indication of liver transplantation for hepatocellular carcinoma"
10.3760/cma.j.issn.0254-1785.2013.09.003
- VernacularTitle:“上海标准”在肝癌肝移植适应证中应用13年的回顾分析
- Author:
Jia FAN
;
Jian ZHOU
;
Yang XU
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Liver transplantation;
Criteria;
Indication;
Survival rate
- From:
Chinese Journal of Organ Transplantation
2013;34(9):521-523
- CountryChina
- Language:Chinese
-
Abstract:
Objective To reevaluate Shanghai Criteria of liver transplantation (LT) for hepatocellular carcinoma (HCC).Method We evaluated the outcome of 433 consecutive patients with HCC who underwent LT from 2001 to 2013 at Zhong shan Hospital,Fudan University.The Kaplan Meier product-limit method with log rank test was used to evaluate survival rate according to different Criteria.Result The 5-year overall survival (OS) rate and relapse-free survival (RFS) rate were as follows:Milan Criteria (n =169; 72.5％ and 79.0％),UCSF Criteria (n =223; 68.2％ and 75.7％) ;Shanghai Criteria (n =255; 65.9％ and 70.6％) ; Pittsburgh Criteria (n =419,55.6％ and 61.2％).There was no significant difference in the 5 year OS and RFS between Shanghai Criteria group and Milan Criteria group (P＞0.05).Conclusion Shanghai Criteria,which modestly expanded current criteria while still preserving similar long term survival,could be more fit for the situation of China.
