Association of apolipoprotein E with diabetic nephropathy in type 2 diabetic patients
10.3760/cma.j.issn.1000-6699.2013.10.014
- VernacularTitle:2型糖尿病患者载脂蛋白E水平与糖尿病肾病的关系研究
- Author:
Jingcheng WU
;
Xiaohua LI
;
Yongde PENG
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy;
Apolipoprotein E;
Diabetes mellitus,type 2
- From:
Chinese Journal of Endocrinology and Metabolism
2013;29(10):879-881
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] This retrospective analysis showed that the level of apolipoprotein E was significantly higher in diabetic nephropathy group compared with normal albuminuria group [50.4 (40.8,65.9) vs 46.2 (38.6,56.8)mg/L,P＜0.01].Difference in urinary albumin to creatinine ratio (ACR) among the groups based on the tertile of apolipoprotein E were significant (P＜ 0.01).Multiple linear regression analysis demonstrated that apolipoprotein E was independently associated with ACR (β =0.14,P＜0.05).
