Analysis on six cases of tertiary hyperparathyroidism and literature review

VernacularTitle:三发性甲状旁腺功能亢进症六例分析并文献复习
Author: Aihua JIA ; Hongquan DU ; Yuhong LI ; Junlong XU ; Guangzhen ZHANG
Publication Type:Journal Article
Keywords: Tertiary hyperparathyroidism; Parathyroid hormone; Pathology
From: Chinese Journal of Endocrinology and Metabolism 2013;29(9):795-798
CountryChina
Language:Chinese
Abstract: The data of 6 patients with tertiary hyperparathyroidism were retrospectively analyzed.The first symptom in 3 patients was bone ache,1 with lower extremity weakness,1 with swelling of lower limbs,and 1 with increase serum alkaline phosphatase.5 patients had past history of renal failure,1 case suffered from severe intestinal malabsorption,and 4 of them had renal transplantation.X-ray showed subperiosteal bone resorption,bone demineralization,or cellulose osteitis.5 subjects presented with osteoporosis,and 1 of them had fractures.Left atrioventricular membrane calcification and gluteal calcification were found in each of 2 cases.4 patients suffered from hypercalcaemia,2 patients with normal serum calcium,4 with hypophosphataemia,and 6 with high levels of PTH.Pathological results showed adenoma in parathyroid gland in 4 patients and enlarged parathyroid glands in 2 patients.Serum calcium and PTH levels returned to normal after operation and calcium supplement.