Study on CXCL5 gene polymorphisms in obese patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2013.09.009
- VernacularTitle:2型糖尿病肥胖患者CXCL5基因多态性的研究
- Author:
Yanru ZHAO
;
Ximing QI
;
Fuzai YIN
;
Bo LIU
;
Yu ZHOU
;
Wen LIU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
CXCL5;
Polymorphisms,gene;
Obesity
- From:
Chinese Journal of Endocrinology and Metabolism
2013;29(9):772-773
- CountryChina
- Language:Chinese
-
Abstract:
The association between CXCL5 gene polymorphism and obese patients with type 2 diabetes mellitus (T2DM) was explored.The distribution of CXCL5 gene promoter region-156G/C polymorphism revealed no significant difference between normal control group and T2DM group (P＞0.05).The frequency of C allele gene in obesity group was higher than that in non-obesity group(P＜0.05).The results suggest that the CXCL5 promoter gene -156G/C polymorphsim has no relation with T2DM,but it is a risk factor for obesity.
