Progress of research in adrenal cortical cells model
10.3760/cma.j.issn.1000-6699.2013.08.026
- VernacularTitle:肾上腺皮质细胞模型研究进展
- Author:
Zhiqiang PAN
;
Zhaoqin FANG
- Publication Type:Journal Article
- Keywords:
Adrenal cortex;
Cell lines;
Cell strains;
Steroid hormone
- From:
Chinese Journal of Endocrinology and Metabolism
2013;29(8):730-734
- CountryChina
- Language:Chinese
-
Abstract:
This paper describes the biological characteristics of human and mouse adrenal cortical carcinoma cell lines and presents research progress made in rat and bovine primary cultured adrenal cortical cells.The effect of angiotensin Ⅱ,potassium,adrenocorticotropic hormone and cAMPon different adrenal cortical cell lines were compared and analyzed,regarding the differences of steroid hormone secreted.The article suggests that it is necessary to develop and establish some ideal adrenal cortex cell models for furtherstudying the mechanisms of steroid hormone synthesis and secretion.
