Clinical effect of methylprednisolone and budesonide suspension inhalation on relieving postextubation throat complications in patients undergoing tracheal intubation
10.3760/cma.j.issn.0254-9026.2013.10.008
- VernacularTitle:甲基强的松龙联合布地奈德雾化预防气管插管拔管后咽喉部不适的临床观察
- Author:
Huilin LIU
;
Lei LI
;
Qingbian MA
- Publication Type:Journal Article
- Keywords:
Glucocorticoids;
Intubation,intratracheal
- From:
Chinese Journal of Geriatrics
2013;32(10):1055-1057
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the difference in the incidence of postextubation throat complications between severe patients treated with methylprednisolone intravenously with and without budesonide suspension inhalation immediately after postextubation.Methods 75 patients with tracheal intubation were divided into group A (n=36,patients received methylprednisolone 40 mg intravenously before extubation) and group B (n=39,patients received methylprednisolone 40 mg intravenously before extubation and budesonide suspension inhalation 1 mg immediately after extubation).Postextubation thoat complications including sore throat,hoarseness and laryngeal edema were observed in the two groups.Clinical efficacies in the two groups were analyzed.Results The incidences of sore throat,hoarseness and laryngeal edema after extubation were 50.0％ (18/ 36),55.6％ (20/36) and 5.6％ (2/36) respectively in group A and 30.8％ (12/39),35.7％ (14/ 39) and 2.6％ (1/39) respectively in group B.There were no significant differences in the incidences of sore throat,hoarseness and laryngeal edema after extubation between the two groups,but the tendencies of complication incidences were decreased in group B as compared with group A.Conclusions The application of intravenous methylprednisolone before extubation and budesonide suspension inhalation after extubation can reduce the incidences of sore throat,hoarseness and laryngeal edema after extubation.
