Relationship between serum uric acid and metabolism syndrome in community-based elderly population in Beijing: a cross-sectional survey
10.3760/cma.j.issn.0254-9026.2013.11.032
- VernacularTitle:北京社区老年人群代谢综合征与血尿酸关系的横断面研究
- Author:
Shaochen GUAN
;
Zhe TANG
;
Xianghua FANG
;
Xiaoguang WU
;
Hongjun LIU
- Publication Type:Journal Article
- Keywords:
Metabolic syndrome X;
Hyperuricemia
- From:
Chinese Journal of Geriatrics
2013;32(11):1246-1249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between serum uric acid (SUA) and metabolism syndrome (MS) in community-based elderly population in Beijing.Methods A community-based and cross-sectional survey on 1821 elderly person was performed in Beijing in 2000.Questionnaire survey,physical examination and blood biochemical tests were conducted.Relationship of MS and its components with SUA was analyzed.Results Among 1821 subjects,there were 365 cases with MS (20.0％) and 1456 cases without MS (80.0％).SUA level was higher in MS group than in non-MS group [(5.20±2.27) μmol/L vs.(4.50±1.44) μmol/L,t=-7.34,P=0.000].All subjects were divided into 4 groups according SUA level:goup 1 (≤3.5μmol/L,n=443),group 2 (3.6 μmol/L-4.4 μmol/L,n=465),group 3 (4.5 μmol/L-5.4 μmol/L,n=446) and group 4 (≥5.5 μmol/L,n=467).SUA level was increased along with the increased BMI,TG,TC,LDL-C levels,and decreased along with the decreased HDL-C level,which had significant differences (F=43.07,9.32,22.36,8.19,9.39,all P＜0.001).There were significant distribution differences in MS components numbers in the 4 groups (x2=73.62,P=0.000).After adjusting for age,sex,residential,education level,marriage,smoking,drinking and exercise habits,logistic regression analysis showed that MS was related with SUA level,and the risk of MS was increased along with the increased SUA level.Conclusions MS is correlated with SUA level in elderly people.SUA level should be observed and controlled effectively in the elderly.
