Analysis of bone mineral density and bone metabolic biochemical markers in 220 elderly men

VernacularTitle:老年男性骨密度与骨代谢指标分析
Author: Yu LU ; Hong GUO ; Bo LIU ; Dongmei LIU
Publication Type:Journal Article
Keywords: Osteoporosis; Bone mineral density; Bone metabolism
From: Chinese Journal of Geriatrics 2013;32(11):1183-1185
CountryChina
Language:Chinese
Abstract: Objective To study the characteristics of bone mineral density and bone metabolism in elderly men.Methods 220 male elderly hospitalized patients were selected and divided into three groups according to age:65-74 years group,75-84 years group and 85-94 years group.Bone mineral density and bone metabolic biochemical makers including serum parathyroid hormone (PTH),bone gla-protein (BGP) and 25-dihydroxy vitamin D (25-OH VD) were detected.Results The prevalence of osteoporosis was increased along with ageing in three groups (6.8％,12.0％ vs.22.9％,respectively,F=4.986,P＜0.05).The characteristics of bone metabolism showed that serum PTH level was increased and serum levels of BGP,25-OH VD were decreased along with ageing (F =4.986,3.245,5.997,all P＜0.05),and the levels of BGP,25-OH VD were generally decreased in elderly men.Conclusions The prevalence of osteoporosis is high in elderly men.Bone metabolism can be used as the auxiliary index for osteoporosis risk assessment,which is helpful for the early diagnosis of primary osteoporosis.