Cholestatic Hepatitis and Thrombocytosis in a Secondary Syphilis Patient.
10.3346/jkms.2010.25.11.1661
- Author:
Gi Hyun KIM
1
;
Byeong Uk KIM
;
Ju Hee LEE
;
Yong Heok CHOI
;
Hee Bok CHAE
;
Seon Mee PARK
;
Sei Jin YOUN
;
Ji Yeoun LEE
;
Tae Young YOON
;
Rohyun SUNG
Author Information
1. Department of Internal Medicine, Chungbuk National University, College of Medicine and Medical Research Institute, Cheongju, Korea. hbchae@chungbuk.ac.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Hepatitis;
Syphilis, Cutaneous;
Thrombocytosis
- MeSH:
Acute Disease;
Adult;
Alkaline Phosphatase/blood;
Bilirubin/blood;
Epidermis/pathology;
Hepatitis/*diagnosis/etiology/pathology;
Humans;
Jaundice;
Male;
Penicillin G Benzathine/therapeutic use;
Syphilis/*complications;
Syphilis Serodiagnosis;
Thrombocytosis/*etiology;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2010;25(11):1661-1664
- CountryRepublic of Korea
- Language:English
-
Abstract:
The incidence of acute hepatitis in syphilis patient is rare. First of all, our patient presented with hepatitis comorbid with thrombocytosis. To our knowledge, this is only the second report of syphilitic hepatitis with thrombocytosis. The 42-yr-old male complained of flulike symptoms and skin eruptions on his palms and soles. Laboratory findings suggested an acute hepatitis and thrombocytosis. Serologic test results were positive for VDRL. He recovered from his symptoms and elevated liver related enzymes with treatment. Because syphilitic hepatitis can present without any typical signs of accompanying syphilis, syphilis should be considered as a possible cause in acute hepatitis patients.
