CT appearances and pathologic correlation of primary pulmonary leiomyoma

VernacularTitle:肺原发性平滑肌瘤CT征象及病理对照分析
Author: Zongqiong SUN ; Lin CHEN ; Feng HE ; Guohou XU ; Li LU ; Jianguo YUE ; Linfang JIN
Publication Type:Journal Article
Keywords: Lung neoplasms; Leiomyoma; Tomography,X-ray computed
From: Chinese Journal of Radiology 2013;47(9):805-807
CountryChina
Language:Chinese
Abstract: Objective To analyze the CT features of primary pulmonary leiomyoma (PPL) and improve the diagnostic ability of PPL.Methods The CT findings and clinical characteristics were retrospectively analyzed in 6 patients with PPL proved by pathology,and the related literatures were reviewed.Results Six PPLs were single lesion from 3.0 to 8.5 cm in size,the shape was round or oval with extremely smooth margin.On CT plain scan,the CT values of all PPL lesions were 25-33 HU,4 lesions presented homogeneous moderate enhancement (40-60 HU) and 2 lesions presented inhomogeneous enhancement after contrast administration.A solid lesion showed obviously patchy enhancement with cystic degeneration,1 lesion presented ring enhancement.All lesions were benign histopathologically,the leiomyoma cells showed spindle shaped or in bundles with pseudocapsule,and with hyaline degeneration in 1 case.Smooth Muscle Actin (SMA) were all marked positive on immunohistochemistry.Conclusions CT findings of PPL have some characteristics,but lack of specificity,the final diagnosis still relies on pathological examination.