Value of real-time elastography guided transperineal prostate biopsies in improving prostate cancer detection rate
10.3760/cma.j.issn.1004-4477.2013.10.017
- VernacularTitle:实时弹性成像引导经会阴前列腺穿刺活检在提高前列腺癌检出率中的作用
- Author:
Yunkai ZHU
;
Yaqing CHEN
;
Tingyue QI
;
Jun JIANG
;
Jun QI
;
Lifeng WANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Prostatic neoplasms;
Biopsy,needle;
Elastography
- From:
Chinese Journal of Ultrasonography
2013;22(10):880-884
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the utility of elastography guided biopsies in men undergoing transrectal ultrasound-guided transperineal prostate biopsies.Methods A total of 108 consecutive patients suspicious for prostate cancer due to elevated serum prostate specific antigen level or abnormal digital rectal examination were enrolled in this prospective study.All patients underwent combined elastography-targeted and 10 core-systematic transperineal biopsy.The impact of elastography-targeted biopsies on the prostate cancer detection rate was analyzed in comparison with prostate biopsy pathology.Results The overall prostate cancer detection rate was 49.1％ (53/108).The prostate cancer detection rate of systematic biopsy was 35.2％(38/108).The increase in cancer detection rate by elastography-targeted biopsies was 13.9％(15/108,P =0.039).A total of 1296 cores were sampled among 108 patients,including 1080 systematic biopsy cores and 216 targeted biopsy cores.The positive rate of targeted biopsy was significantly higher than systematic biopsy (50.9％ vs 14.1％,P ＜0.0001).Conclusions Prostate cancer detection rate could be significantly improved by elastography targeted transperineal biopsy.
