Cloning of the gene encoding human interleukin-2
- Author:
Nguyen Nam Long
- Publication Type:Journal Article
- Keywords:
Interleukin 2
- MeSH:
Interleukins;
Human;
Genes
- From:Journal of Vietnamese Medicine
2005;310(5):26-30
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Study on cloning of the gene encoding human interleukin-2 with gene produce method by RT-PCR. Results: cloned and determine order of gene fragment encoded IL-2 that having 333pp size (133 amino acids) from total RNA of human spleen by RT-PCR. The results of analysis order of cloned IL2 gem showed that there were 2 changes of single nucleotide (A36G, G54T) in comparison with that of the NP-000577 order registered in NCBI GenBank A36G and G54T. However, these changes did not make changes in amino acid sequence of the cloned II-2 gene