Diagnostic value of virtual tissue quantification in differentiating benign or malignant of breast tumors

VernacularTitle:声脉冲辐射力弹性成像诊断乳腺肿瘤的价值
Author: Senyin XU ; Xiafang WU
Publication Type:Journal Article
Keywords: Elasticity imaging techniques; Ultrasonography; Breast neoplasms/diagnosis; Diagnosis,differential
From: Journal of Chinese Physician 2013;15(9):1199-1201
CountryChina
Language:Chinese
Abstract: Objective To investigate the value of acoustic radiation force impulse (ARFI) in differential diagnosis between benign and malignant breast tumors.Methods Virtual touch tissue imaging (VTI) and virtual touch tissue quantification (VTQ) of ARFI elastography were used to estimate the properties and extent and measured the shear wave velocities (SWV) of the breast tumors,respectively.Results The mean SWV of breast cancer and benign lesion were (7.84 ±2.51)m/s and (2.79 ±0.92)m/s.There was significant difference in the SWV between benign and malignant breast tumors (P ＜ 0.01).The area under curve (AUC) of receiver operating characteristic (ROC) curve of the SWV in differentiating benign from malignant breast tumors was 0.886.With SWV 4.4 as cut-off,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value in the diagnosis of malignant from benign breast tumors were 78.7％,100％,91.7％,100％,88％,respectively.Conclusions ARFI elastography could reflect the elastic characteristics of breast tumors,which might be useful for the differential diagnosis between benign and malignant breast tumors.