Clinical value of serum HDL-C in the evaluation of synthetic function of the liver
10.3760/cma.j.issn.1008-6706.2013.21.034
- VernacularTitle:血清高密度脂蛋白胆固醇水平检测对肝脏合成功能的评价作用
- Author:
Qingsong CHEN
;
Wen XIE
;
Jianzhong CHU
- Publication Type:Journal Article
- Keywords:
Hepatitis,Liver cirrhosis,Liver neoplasms;
High density lipoprotein cholesterol
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(21):3276-3277
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of serum high density lipoprotein cholesterol (HDL-C)in the evaluation of synthetic function of the patients with liver diseases.Methods Abbott Aeroset automatic biochemical analyzer was used to detect serum HDL-C level in control group (30 cases) and liver disease group(87 cases).T test was used to analyze the differences of serum HDL-C level in liver disease group and control group,different liver disease groups and control group,and different liver disease groups.Results HDL-C level was (1.28 ±0.20)mmol/L in the control group,(0.77 ± 0.15)mmol/L in the liver disease group,and (0.81 ± 0.13)mmol/L in the hepatitis group,(0.68 ± 0.14)mmol/L in the liver cirrhosis group,(0.54 ± 0.05)mmol/L in the liver cancer group.The HDL-C level in liver disease group and hepatitis group,liver cirrhosis group,liver cancer group was significantly lower than that in the control group(t =15.5569,14.2463,45.4393,25.6344,all P ＜ 0.01).The HDL-C level in liver cirrhosis group and liver cancer group was significantly lower than that in hepatitis group (t =3.6583,16.9057,all P ＜ 0.01).The HDL-C level in liver cancer group was significantly lower than that in liver cirrhosis group(t =4.4103,P ＜ 0.01).Conclusion Serum HDL-C level can be used to evaluate synthetic function of the liver,the lower of serum HDL-C level,the more serious liver synthesis function is impaired.
