Therapeutic effect of LEEP in the treatment of patients with cervical intraepithelial neoplasia and its influence on pregnancy outcome
10.3760/cma.j.issn.1008-6706.2013.21.013
- VernacularTitle:宫颈电环切术治疗宫颈上皮内瘤变的疗效及对妊娠结局的影响
- Author:
Lili WU
;
Li HUANG
- Publication Type:Journal Article
- Keywords:
Loop electrosurgical excision procedure;
Cervical intraepithelial neoplasia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(21):3229-3231
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic effect of loop electrosurgical excision procedure (LEEP)in the treatment of patients with cervical intraepithelial neoplasia (CIN) and its influence on pregnancy outcome.Methods 62 women with CIN who underwent LEEP were selected as treatment group,and 63 women with CIN who did not undergo LEEP in the same period were selected as control group.Then the curative effect and the pregnancy outcome were observed.Results The total effective rate was 93.65％ in the treatment group and 76.19％ in the control group,the difference was significant (x2 =7.034,P ＜ 0.01).The operation blood loss,operation time and the day of colporrhagia after operation in the treatment group were less than those in the control group(all P ＜ 0.05).There were no significant differences in the gestational age,incidence rates of abortion and cesarean section between the two groups (all P ＞ 0.05),while there were significant difference in the incidences of preterm delivery,premature rupture of membrane and low birth weight infant (all P ＜ 0.05).Conclusion LEEP is an effective treatment for patients with CIN,which can increase the incidence rates of preterm delivery,premature rupture of membrane and low birth weight infant,but not increase the gestational age,incidence rates of abortion and cesarean section.
