The value of detection of measles antibody in cord blood for estimation of the crowd measles antibody level
10.3760/cma.j.issn.1673-4904.2013.27.004
- VernacularTitle:检测脐血中的麻疹抗体滴度对评估人群整体麻疹抗体水平的价值研究
- Author:
Baoxia SUN
;
Xiuxia SUN
;
Yuan ZHOU
;
Yantian WANG
- Publication Type:Journal Article
- Keywords:
Measles virus;
Fetal blood;
Antibodies
- From:
Chinese Journal of Postgraduates of Medicine
2013;36(27):10-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between umbilical cord blood tire mass measles antibody and maternal measles antibody degrees,in order to evaluate the crowd measles antibody level and provide scientific basis for lasting elimination of measles.Methods Collected 40 cases of healthy maternal venous blood and their paired cord blood,enzyme-linked immunosorbent assay (ELISA) was used for the detection of measles antibody.Results In the 1:200 level,mother blood and umbilical cord blood of measles antibody level were 11.29 ±4.81 and 12.76 ± 5.32,in the 1:800 level were 6.89 ±4.11 and 8.28 ± 4.91,both had correlation (r =0.575,0.618,P ＜0.05).Conclusions Measles antibody titers of maternal venous blood and paired cord blood are highly correlated.The results show that maternal measles antibodies could pass through the placenta to the daughter,and measles antibody titers detected in umbilical cord blood can be used not only to assess the maternal measles antibodies level,but also can be used as a predictor of measles antibody levels for newborns and young children.
