Optimization of immunosuppressive therapy after liver transplantation
10.3760/cma.j.issn.1673-9752.2013.09.004
- VernacularTitle:优化肝移植术后免疫抑制治疗方案
- Author:
Zhanyu YANG
;
Tengqian TANG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Immunosuppressant;
Individualized therapy
- From:
Chinese Journal of Digestive Surgery
2013;12(9):652-654
- CountryChina
- Language:Chinese
-
Abstract:
The toxic effects of immunosuppressants are often dangerous factors which influence long-term survival of recipients.Individualized immunosuppressive therapy has been a hotspot and difficulty for comprehensive treatment of liver transplantation.Immunosuppressive therapy has been gradually developed to pursue long-term survival for receipients and graft,minimized side effects of immunosuppressants,optimized quality of life of patients,and reduce the economic burden of patients.Through consideration of patient's pathophysiological state,understanding the characteristics and side effects of various immunosuppressive,appropriate choose of the immune inhibitor,correct evaluation of immune state of recipients and graft,minimization of drug doses,individualized dosing regimen could be successfully carried out.