Clinical analysis of pulmonary embolism patients with plasma D-dimer ＜ 500 μg/L
10.3760/cma.j.issn.1671-0282.2013.09.020
- VernacularTitle:血浆D-二聚体＜500μg/L肺栓塞患者临床分析
- Author:
Fang LIU
;
Jun FENG
- Publication Type:Journal Article
- Keywords:
Pulmonary embolism;
D-dimer;
Wells score
- From:
Chinese Journal of Emergency Medicine
2013;22(9):1021-1024
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of plasma D-dimer ＜ 500 μg/L level in diagnosis of pulmonary thromboembolism occurred in patients.Methods The clinical data of the patients with pulmonary embolism confirmed by imaging examination with plasma D-dimer levels ＜ 500 μg/L admitted from January 1st 2008 to June 30th 2011 were analyzed retrospectively.Results Totally,there were ten pulmonary embolism patients with plasma D-dimer levels ＜ 500 μg/L.The 10 eligible patients were assessed for the possibility of pulmonary embolism by using the Wells score (i.e.Wells clinical pretest probability prediction model).Of them,0 cases was evaluated as low clinical pretest probability (grade ＜2),7 cases as moderate clinical pretest probability (grade 2 ～6) and 3 cases as high clinical pretest probability (grade ＞ 6).Conclusions Pulmonary thromboembolism was easily misdiagnosed for lacking specific clinical manifestations and the missed diagnosis in patients caused high mortality,so it was difficult to exclude acute pulmonary embolism simply depending on the D-dimer levels ＜ 500 μg/L.Therefore,in case of plasma D-dimer levels less than 500 μ g/L,the possibility of pulmonary embolism cannot be ruled out in patients with moderate or high Wells clinical pretest probability.
