Research progress in the tumorigenicity of embryonic stem cells

VernacularTitle:胚胎干细胞致瘤性研究进展
Author: Ling WANG ; Wenjie ZHANG
Publication Type:Journal Article
Keywords: Embryonic stem cells; Tumorigenicity; Residual
From: International Journal of Biomedical Engineering 2013;36(5):299-302
CountryChina
Language:Chinese
Abstract: Stem cells research is the hotspot in the field of biological science and medicine.Stem cells can be classified into embryonic stem cells and somatic stem cells.Embryonic stem cells derived from early preimplantation embryo have the pluripotent and unlimited self-renewal capacity.They are an attractive source for tissue engineering,gene therapy,basic study of developmental biology and so on.However,such therapies carry a risk of teratoma formation,and may contribute to the functional failure of the graft.Here,we discuss the reasons for the formation of teratoma and the solutions to this problem.