Predictors for intravenous immunoglobulin resistance and coronary artery leisions in Kawasaki disease
10.3760/cma.j.issn.1673-4408.2013.06.024
- VernacularTitle:川崎病丙种球蛋白耐药及冠状动脉损伤早期预测指标的研究进展
- Author:
Chunhong XIE
- Publication Type:Journal Article
- Keywords:
Kawasaki disease;
Coronary artery lesion;
Intravenous immunoglobulin resistance;
Prediction
- From:
International Journal of Pediatrics
2013;40(6):625-628
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease(KD) is an acute,systemic vasculitis syndrome that primarily affects coronary arteries.The long-term prognosis depends on the severity of coronary artery leisions(CAL).Treatment with high-dose intravenous immunoglobulin(IVIG) within 10 days of the onset of fever is proven to decrease the incidence of CAL.Patients with IVIG resistance is at a high risk to be affected by CAL.How to predict IVIG resistance and CAL in the early stage is helpful for improving the outcome of Kawasaki disease.Thus,predictors of IVIG resistance and CAL for KD were reviewed in this article.
