Evaluation of major methods of hemoglobin analysis
10.3760/cma.j.issn.1009-9158.2013.10.023
- VernacularTitle:血红蛋白分析的方法学评价
- Author:
Yong XIA
;
Likuan XIONG
- Publication Type:Journal Article
- Keywords:
Hemoglobinometry;
Electrophoresis,agar gel;
Chromatography,high pressure liquid;
Electrophoresis,capillary;
Mass spectrometry
- From:
Chinese Journal of Laboratory Medicine
2013;36(10):950-953
- CountryChina
- Language:Chinese
-
Abstract:
Hemoglobinopathy is a kind of hereditary hematonosis caused by the disproportion among normal hemoglobins or formation of abnormal hemoglobins.Hemoglobin analysis plays an important role in screening and diagnosing hemoglobinopathy.Emerging methods have been applied continuously to hemoglobinometry since the early 20th century.Nowadays,agarose gel electrophoresis,high performance liquid chromatography and capillary electrophoresis are widely used with mass spectrometry as the latest applied method.All these methods have their own features.Appropriate combination of these methods will lead to more scientific and reliable results.
