Clinical effects of botulinum toxin type A injection guided by electromyography and electrical stimulation for the treatment of upper limb spasticity after stroke
10.3760/cma.j.issn.0254-1424.2013.09.011
- VernacularTitle:肌电图联合电刺激引导注射肉毒毒素治疗脑卒中后上肢痉挛的疗效观察
- Author:
Bojun HAN
;
Shanshan HONG
;
Minzhi LU
;
Zhigang SUN
;
Feng HAN
;
Dinghua LIU
- Publication Type:Journal Article
- Keywords:
Stroke;
Spasticity;
Electromyography;
Botulinum toxin type A
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2013;35(9):716-719
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of botulinum toxin type A (BTX-A) injections guided by electromyography in combination with electrical stimulation in the treatment of upper limb spasticity poststroke.Methods Forty-five patients with upper limb spasticity following stroke were recruited.They received multiple intra-muscular BTX-A injections guided by electromyography and electrical stimulation.Rehabilitation training was administered after the BTX-A injections.The results were assessed using the modified Ashworth scale (MAS),the Fugl-Meyer upper limb assessment (FMA),active range of movement (AROM) and the modified Barthel index (MBI).All the assessments were performed at the baseline,and then 1 week,2 weeks,1 month,and 3 months after the injections.Results Compared with the baseline scores the MAS,FMA,AROM and MBI results had all obviously improved by 2 weeks after the BTX-A injections.Compared with 2 weeks after the injections,the FMA and AROM scores at 1 month were significantly higher and there were further significant improvements at 3 months.No patient demonstrated obvious side effects from the therapy.Conclusion BTX-A injection guided by electromyography and electrical stimulation is safe and has definite beneficial effects on upper limb spasticity after stroke.
