Relationship of congenital urogenital abnormalities and chromosomal abnormalities: a report of 200cases
10.3760/cma.j.issn.1671-7368.2013.10.025
- VernacularTitle:泌尿生殖系统先天畸形患者200例染色体畸变的检测
- Author:
Lina ZHU
;
Xiao YANG
;
Ning MA
;
Hao LI
;
Jia GUO
;
Xue BAI
;
Chunzhi WANG
- Publication Type:Journal Article
- Keywords:
Chromosome aberrations;
Sex reversal syndrome
- From:
Chinese Journal of General Practitioners
2013;12(10):839-841
- CountryChina
- Language:Chinese
-
Abstract:
A total of 200 outpatients with congenital urogenital abnormalities were recruited.Peripheral blood from each patient had mixed lymphocyte culture and chromosome karyotype was analyzed.Among them,22 (11%) cases showed abnormal chromosomal karyotypes.The aberrations included abnormal chromosome number (n =13),abnormal chromosome structure (n =8) and sex reversal syndrome (n =1).Chromosomal aberrations are important causative factors of congenital urogenital abnormalities.