Relationship of congenital urogenital abnormalities and chromosomal abnormalities: a report of 200cases

VernacularTitle:泌尿生殖系统先天畸形患者200例染色体畸变的检测
Author: Lina ZHU ; Xiao YANG ; Ning MA ; Hao LI ; Jia GUO ; Xue BAI ; Chunzhi WANG
Publication Type:Journal Article
Keywords: Chromosome aberrations; Sex reversal syndrome
From: Chinese Journal of General Practitioners 2013;12(10):839-841
CountryChina
Language:Chinese
Abstract: A total of 200 outpatients with congenital urogenital abnormalities were recruited.Peripheral blood from each patient had mixed lymphocyte culture and chromosome karyotype was analyzed.Among them,22 (11％) cases showed abnormal chromosomal karyotypes.The aberrations included abnormal chromosome number (n =13),abnormal chromosome structure (n =8) and sex reversal syndrome (n =1).Chromosomal aberrations are important causative factors of congenital urogenital abnormalities.